As a science-based organisation, GABA Labs regularly collaborates with research institutions internationally. Current Requests for Proposals are:
As part of the Company’s objective to develop functional alternatives to alcohol, GABALabs have a range of key products both natural and synthetic that work by modulating the GABAergic system to support conviviality. We are seeking research collaborators to provide a programme of work that would be able to provide extended pharmacological/physiological profiles of these products in in vitro systems. Ideally this programme would cover measures of direct agonism of the GABAergic systems as well as potential positive allosteric modulation properties at other sites on the GABAA receptor (GABAAR): neurosteroid, BDZ, etc (Belelli et al.2021). We invite proposals that include pharmacological techniques, specifically radioligand binding and electrophysiology, to profile in vitro native and recombinant GABAAR expression systems to meet this goal. In addition, profiles at other health relevant off-targets e.g. HERG K+ channels would be welcome.
We invite scientists from the UK to submit competitive testable research proposals that meet these criteria for profiling these products at the GABAergic system. Submit outline proposals (no more than 2 sides of A4) by e-mail (see below) with indicative budgets, to GABALabs no later than 30 May 2025, 11:59 pm BST.
Full details available here (pdf).
Submit proposals to: research.proposals@gabalabs.com with subject line to include “Request #2: Receptor Selectivity -April-2025”